1TZI

Crystal Structure of the Fab YADS2 Complexed with h-VEGF

Summary for 1TZI

Entry DOI	10.2210/pdb1tzi/pdb
Related	1TZH
Descriptor	Fab YADS2 Light Chain, Fab YADS2 Heavy Chain, Vascular endothelial growth factor A (3 entities in total)
Functional Keywords	phage display, antibody library, protein engineering, immune system
Biological source	Mus musculus (house mouse) More
Cellular location	Secreted: P15692
Total number of polymer chains	3
Total formula weight	58712.56
Authors	Fellouse, F.A.,Wiesmann, C.,Sidhu, S.S. (deposition date: 2004-07-10, release date: 2004-08-31, Last modification date: 2023-08-23)
Primary citation	Fellouse, F.A.,Wiesmann, C.,Sidhu, S.S. Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition Proc.Natl.Acad.Sci.USA, 101:12467-12472, 2004 Cited by PubMed: 15306681 DOI: 10.1073/pnas.0401786101 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation