1TZH
Crystal Structure of the Fab YADS1 Complexed with h-VEGF
Summary for 1TZH
Entry DOI | 10.2210/pdb1tzh/pdb |
Related | 1tzi |
Descriptor | Vascular endothelial growth factor A, Fab YADS1 Light Chain, Fab YADS1 Heavy Chain, ... (4 entities in total) |
Functional Keywords | phage display, antibody library, protein engineering, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P15692 |
Total number of polymer chains | 6 |
Total formula weight | 118570.13 |
Authors | Fellouse, F.A.,Wiesmann, C.,Sidhu, S.S. (deposition date: 2004-07-09, release date: 2004-08-31, Last modification date: 2023-08-23) |
Primary citation | Fellouse, F.A.,Wiesmann, C.,Sidhu, S.S. Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition Proc.Natl.Acad.Sci.USA, 101:12467-12472, 2004 Cited by PubMed: 15306681DOI: 10.1073/pnas.0401786101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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