1TTV

NMR Structure of a Complex Between MDM2 and a Small Molecule Inhibitor

Summary for 1TTV

• Entry DOI: 10.2210/pdb1ttv/pdb
• Related: 1RV1 1YCQ
• NMR Information: BMRB: 6248
• Descriptor: Ubiquitin-protein ligase E3 Mdm2, 1-{[4,5-BIS(4-CHLOROPHENYL)-2-(2-ISOPROPOXY-4-METHOXYPHENYL)-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]CARBONYL}PIPERAZINE (2 entities in total)
• Functional Keywords: mdm2, protein-protein interaction, ligase
• Biological source: Xenopus laevis (African clawed frog)
• Cellular location: Nucleus, nucleoplasm (By similarity): P56273
• Total number of polymer chains: 1
• Total formula weight: 12774.39

Authors

Fry, D.C.,Emerson, S.D.,Palme, S.,Vu, B.T.,Liu, C.M.,Podlaski, F. (deposition date: 2004-06-23, release date: 2005-01-04, Last modification date: 2021-10-27)

• Primary citation: Fry, D.C.,Emerson, S.D.,Palme, S.,Vu, B.T.,Liu, C.M.,Podlaski, F.; NMR structure of a complex between MDM2 and a small molecule inhibitor.; J.Biomol.Nmr, 30:163-173, 2004; PubMed: 15557803; DOI: 10.1023/B:JNMR.0000048856.84603.9b

Experimental method

SOLUTION NMR