1T8U
Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP and tetrasaccharide substrate
Summary for 1T8U
Entry DOI | 10.2210/pdb1t8u/pdb |
Related | 1BFB 1HY3 1S6T 1T8T |
Descriptor | heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, SULFATE ION, ... (6 entities in total) |
Functional Keywords | alpha-beta motif, substrate-binding cleft, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 64409.16 |
Authors | Moon, A.F.,Edavettal, S.C.,Krahn, J.M.,Munoz, E.M.,Negishi, M.,Linhardt, R.J.,Liu, J.,Pedersen, L.C. (deposition date: 2004-05-13, release date: 2004-08-31, Last modification date: 2024-04-03) |
Primary citation | Moon, A.F.,Edavettal, S.C.,Krahn, J.M.,Munoz, E.M.,Negishi, M.,Linhardt, R.J.,Liu, J.,Pedersen, L.C. Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1 J.Biol.Chem., 279:45185-45193, 2004 Cited by PubMed: 15304505DOI: 10.1074/jbc.M405013200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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