1SYH
X-RAY STRUCTURE OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 1.85 A RESOLUTION.
Summary for 1SYH
Entry DOI | 10.2210/pdb1syh/pdb |
Related | 1ftj 1ftm 1fw0 1gr2 1m5b 1m5c 1m5e 1mqd 1mqg 1nnp 1SYI |
Descriptor | Glutamate receptor 2, (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID (3 entities in total) |
Functional Keywords | ionotropic glutamate receptor glur2, ligand-binding core, agonist complex, membrane protein |
Biological source | Rattus norvegicus (Norway rat) |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 1 |
Total formula weight | 29460.91 |
Authors | Frandsen, A.,Pickering, D.S.,Vestergaard, B.,Kasper, C.,Nielsen, B.B.,Greenwood, J.R.,Campiani, G.,Gajhede, M.,Schousboe, A.,Kastrup, J.S. (deposition date: 2004-04-01, release date: 2005-03-22, Last modification date: 2023-08-23) |
Primary citation | Frandsen, A.,Pickering, D.S.,Vestergaard, B.,Kasper, C.,Nielsen, B.B.,Greenwood, J.R.,Campiani, G.,Fattorusso, C.,Gajhede, M.,Schousboe, A.,Kastrup, J.S. Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2. Mol.Pharmacol., 67:703-713, 2005 Cited by PubMed: 15591246DOI: 10.1124/mol.104.002931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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