1SSP

WILD-TYPE URACIL-DNA GLYCOSYLASE BOUND TO URACIL-CONTAINING DNA

Summary for 1SSP

• Entry DOI: 10.2210/pdb1ssp/pdb
• Descriptor: 5'-D(*CP*TP*GP*TP*(D1P)P*AP*TP*CP*TP*T)-3', 5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*AP*G)-3', URACIL-DNA GLYCOSYLASE, ... (5 entities in total)
• Functional Keywords: dna glycosylase, dna base excision repair, uracil, dna, protein/dna, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Mitochondrion. Isoform 2: Nucleus: P13051
• Total number of polymer chains: 3
• Total formula weight: 31948.38

Authors

Parikh, S.S.,Mol, C.D.,Slupphaug, G.,Bharati, S.,Krokan, H.E.,Tainer, J.A. (deposition date: 1999-04-28, release date: 1999-05-06, Last modification date: 2023-08-02)

• Primary citation: Parikh, S.S.,Mol, C.D.,Slupphaug, G.,Bharati, S.,Krokan, H.E.,Tainer, J.A.; Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.; EMBO J., 17:5214-5226, 1998; PubMed: 9724657; DOI: 10.1093/emboj/17.17.5214

Experimental method

X-RAY DIFFRACTION (1.9 Å)