1RKP
Crystal structure of PDE5A1-IBMX
Summary for 1RKP
Entry DOI | 10.2210/pdb1rkp/pdb |
Related | 1RKO |
Descriptor | cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | pde5a, viagra, ibmx, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 38100.49 |
Authors | Huai, Q.,Liu, Y.,Francis, S.H.,Corbin, J.D.,Ke, H. (deposition date: 2003-11-22, release date: 2004-03-30, Last modification date: 2024-04-03) |
Primary citation | Huai, Q.,Liu, Y.,Francis, S.H.,Corbin, J.D.,Ke, H. Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor IBMX suggest a conformation determinant of inhibitor selectivity J.Biol.Chem., 279:13095-13101, 2004 Cited by PubMed: 14668322DOI: 10.1074/jbc.M311556200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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