1RKP
Crystal structure of PDE5A1-IBMX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cGMP-specific 3',5'-cyclic phosphodiesterase | polymer | 326 | 37788.5 | 1 | UniProt (O76074) Pfam (PF00233) In PDB | Homo sapiens (human) | CGB-PDE, cGMP-binding cGMP-specific phosphodiesterase |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | 3-ISOBUTYL-1-METHYLXANTHINE | non-polymer | 222.2 | 1 | Chemie (IBM) | |||
| 5 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 535 - 860 (UniProt: O76074)
| PDB | External Database | Details |
|---|---|---|
| Leu 778 | Ile 778 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37788.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 312.0 | |
| All* | Total formula weight | 38100.5 |
