1R9Y
Bacterial cytosine deaminase D314A mutant.
Summary for 1R9Y
| Entry DOI | 10.2210/pdb1r9y/pdb |
| Related | 1K6W 1R9X 1R9Z 1RA0 1RA5 1RAK 1RB7 |
| Descriptor | Cytosine deaminase, FE (III) ION, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | cytosine deaminase, amino hydrolase, alpha-beta barrel, hexamer, domain swap, d314a mutant, hydrolase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 47988.23 |
| Authors | Mahan, S.D.,Ireton, G.C.,Stoddard, B.L.,Black, M.E. (deposition date: 2003-10-31, release date: 2004-10-05, Last modification date: 2023-08-23) |
| Primary citation | Mahan, S.D.,Ireton, G.C.,Knoeber, C.,Stoddard, B.L.,Black, M.E. Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy. Protein Eng.Des.Sel., 17:625-633, 2004 Cited by PubMed: 15381761DOI: 10.1093/protein/gzh074 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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