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1R2B

Crystal structure of the BCL6 BTB domain complexed with a SMRT co-repressor peptide

Summary for 1R2B
Entry DOI10.2210/pdb1r2b/pdb
Related1R28 1R29
DescriptorB-cell lymphoma 6 protein, Nuclear receptor co-repressor 2 (3 entities in total)
Functional Keywordsbtb domain, hdac complex, b-cell lymphoma, transcriptional repression, transcription
Biological sourceHomo sapiens (human)
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Cellular locationNucleus (By similarity): P41182
Nucleus: Q9Y618
Total number of polymer chains4
Total formula weight33168.30
Authors
Ahmad, K.F.,Melnick, A.,Lax, S.A.,Bouchard, D.,Liu, J.,Kiang, C.L.,Mayer, S.,Licht, J.D.,Prive, G.G. (deposition date: 2003-09-26, release date: 2003-12-23, Last modification date: 2024-02-14)
Primary citationAhmad, K.F.,Melnick, A.,Lax, S.,Bouchard, D.,Liu, J.,Kiang, C.L.,Mayer, S.,Takahashi, S.,Licht, J.D.,Prive, G.G.
Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
Mol.Cell, 12:1551-1564, 2003
Cited by
PubMed: 14690607
DOI: 10.1016/S1097-2765(03)00454-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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