1Q1G
Crystal structure of Plasmodium falciparum PNP with 5'-methylthio-immucillin-H
Summary for 1Q1G
Entry DOI | 10.2210/pdb1q1g/pdb |
Related | 1NW4 |
Descriptor | Uridine phosphorylase putative, SULFATE ION, 3,4-DIHYDROXY-2-[(METHYLSULFANYL)METHYL]-5-(4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)PYRROLIDINIUM, ... (5 entities in total) |
Functional Keywords | transition state complex, transferase |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 6 |
Total formula weight | 187450.59 |
Authors | Shi, W.,Ting, L.M.,Kicska, G.A.,Lewandowicz, A.,Tyler, P.C.,Evans, G.B.,Furneaux, R.H.,Kim, K.,Almo, S.C.,Schramm, V.L. (deposition date: 2003-07-19, release date: 2004-03-16, Last modification date: 2023-08-16) |
Primary citation | Shi, W.,Ting, L.M.,Kicska, G.A.,Lewandowicz, A.,Tyler, P.C.,Evans, G.B.,Furneaux, R.H.,Kim, K.,Almo, S.C.,Schramm, V.L. Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION. J.Biol.Chem., 279:18103-18106, 2004 Cited by PubMed: 14982926DOI: 10.1074/jbc.C400068200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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