1O7D
The structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low pH activation
Summary for 1O7D
Entry DOI | 10.2210/pdb1o7d/pdb |
Descriptor | Lysosomal alpha-mannosidase, ZINC ION, SULFATE ION, ... (12 entities in total) |
Functional Keywords | hydrolase, glycosyl hydrolase family 38, a-mannosidase, lysosomal |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 5 |
Total formula weight | 111487.00 |
Authors | Heikinheimo, P.,Helland, R.,Leiros, H.S.,Leiros, I.,Karlsen, S.,Evjen, G.,Ravelli, R.,Schoehn, G.,Ruigrok, R.,Tollersrud, O.-K.,Mcsweeney, S.,Hough, E. (deposition date: 2002-10-30, release date: 2003-03-20, Last modification date: 2023-12-13) |
Primary citation | Heikinheimo, P.,Helland, R.,Leiros, H.S.,Leiros, I.,Karlsen, S.,Evjen, G.,Ravelli, R.,Schoehn, G.,Ruigrok, R.,Tollersrud, O.-K.,Mcsweeney, S.,Hough, E. The Structure of Bovine Lysosomal Alpha-Mannosidase Suggests a Novel Mechanism for Low-Ph Activation J.Mol.Biol., 327:631-, 2003 Cited by PubMed: 12634058DOI: 10.1016/S0022-2836(03)00172-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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