1O7D

The structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low pH activation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004559	molecular_function	alpha-mannosidase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0006013	biological_process	mannose metabolic process
B	0004559	molecular_function	alpha-mannosidase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0006013	biological_process	mannose metabolic process
C	0003824	molecular_function	catalytic activity
C	0004559	molecular_function	alpha-mannosidase activity
C	0005975	biological_process	carbohydrate metabolic process
C	0006013	biological_process	mannose metabolic process
C	0030246	molecular_function	carbohydrate binding
D	0003824	molecular_function	catalytic activity
D	0004559	molecular_function	alpha-mannosidase activity
D	0005975	biological_process	carbohydrate metabolic process
D	0006013	biological_process	mannose metabolic process
D	0030246	molecular_function	carbohydrate binding
E	0003824	molecular_function	catalytic activity
E	0005975	biological_process	carbohydrate metabolic process
E	0030246	molecular_function	carbohydrate binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"12634058","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12634058","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1O7D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12634058","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1O7D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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