1MZN

CRYSTAL STRUCTURE at 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE

Summary for 1MZN

• Entry DOI: 10.2210/pdb1mzn/pdb
• Related: 1FBY 1MV9 1MVC
• Descriptor: RXR retinoid X receptor, Nuclear receptor coactivator 2, 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID, ... (4 entities in total)
• Functional Keywords: transcription, nuclear receptor, retinoic acid receptors, agonist
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P19793 Q15596
• Total number of polymer chains: 8
• Total formula weight: 115261.50

Authors

Egea, P.F.,Mitschler, A.,Moras, D. (deposition date: 2002-10-09, release date: 2002-10-23, Last modification date: 2023-10-25)

• Primary citation: Egea, P.F.,Mitschler, A.,Moras, D.; Molecular Recognition of Agonist Ligands by RXRs; MOL.ENDOCRINOL., 16:987-997, 2002; PubMed: 11981034; DOI: 10.1210/me.16.5.987

Experimental method

X-RAY DIFFRACTION (1.9 Å)