1MZN
CRYSTAL STRUCTURE at 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | RXR retinoid X receptor | polymer | 240 | 26856.0 | 4 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Retinoic acid receptor RXR-alpha |
| 2 | B, D, F, H (B, D, F, H) | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 4 | UniProt (Q15596) | synthetic construct | GRIP1 |
| 3 | I, J, K, L (A, C, E, G) | 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID | non-polymer | 379.5 | 4 | Chemie (BM6) | |||
| 4 | M, N, O, P, Q... (A, B, C, E, F...) | water | water | 18.0 | 823 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 113743.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1517.9 | |
| All* | Total formula weight | 115261.5 |
