1MVC
Crystal structure of the human RXR alpha ligand binding domain bound to the synthetic agonist compound BMS 649 and a coactivator peptide
Summary for 1MVC
Entry DOI | 10.2210/pdb1mvc/pdb |
Related | 1FBY 1MV9 |
Descriptor | RXR retinoid X receptor, Nuclear receptor coactivator 2, 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID, ... (4 entities in total) |
Functional Keywords | nuclear receptor, retinoic acid, agonist recognition, transcription factor, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P19793 Q15596 |
Total number of polymer chains | 2 |
Total formula weight | 28815.37 |
Authors | Egea, P.F.,Mitschler, A.,Moras, D. (deposition date: 2002-09-24, release date: 2002-10-16, Last modification date: 2023-10-25) |
Primary citation | Egea, P.F.,Mitschler, A.,Moras, D. Molecular Recognition of Agonist Ligands by RXRs MOL.ENDOCRINOL., 16:987-997, 2002 Cited by PubMed: 11981034DOI: 10.1210/me.16.5.987 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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