1MVC
Crystal structure of the human RXR alpha ligand binding domain bound to the synthetic agonist compound BMS 649 and a coactivator peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RXR retinoid X receptor | polymer | 240 | 26856.0 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Retinoic acid receptor RXR-alpha |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) | GRIP1 | |
| 3 | C (A) | 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID | non-polymer | 379.5 | 1 | Chemie (BM6) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28435.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 379.5 | |
| All* | Total formula weight | 28815.4 |
