1M10

Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain

Summary for 1M10

• Entry DOI: 10.2210/pdb1m10/pdb
• Related: 1M0Z
• Descriptor: von Willebrand Factor, Glycoprotein Ib alpha (2 entities in total)
• Functional Keywords: leucine-rich repeat, hemostasis, dinucleotide binding fold, blood clotting
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P04275; Membrane; Single-pass type I membrane protein: P07359
• Total number of polymer chains: 2
• Total formula weight: 56066.29

Authors

Huizinga, E.G.,Tsuji, S.,Romijn, R.A.P.,Schiphorst, M.E.,de Groot, P.G.,Sixma, J.J.,Gros, P. (deposition date: 2002-06-16, release date: 2002-08-28, Last modification date: 2023-10-25)

• Primary citation: Huizinga, E.G.,Tsuji, S.,Romijn, R.A.,Schiphorst, M.E.,de Groot, P.G.,Sixma, J.J.,Gros, P.; Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.; Science, 297:1176-1179, 2002; PubMed: 12183630; DOI: 10.1126/science.107355

Experimental method

X-RAY DIFFRACTION (3.1 Å)