1LX5
Crystal Structure of the BMP7/ActRII Extracellular Domain Complex
Summary for 1LX5
Entry DOI | 10.2210/pdb1lx5/pdb |
Related | 1LXI |
Descriptor | bone morphogenetic protein 7, Activin Type II Receptor, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-4)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | ligand-receptor complex, growth factor-growth factor receptor complex, growth factor/growth factor receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P18075 Membrane; Single-pass type I membrane protein: P27038 |
Total number of polymer chains | 2 |
Total formula weight | 29234.55 |
Authors | Greenwald, J.,Groppe, J.,Kwiatkowski, W.,Choe, S. (deposition date: 2002-06-04, release date: 2003-04-01, Last modification date: 2020-07-29) |
Primary citation | Greenwald, J.,Groppe, J.,Gray, P.,Wiater, E.,Kwiatkowski, W.,Vale, W.,Choe, S. The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly Mol.Cell, 11:605-617, 2003 Cited by PubMed: 12667445DOI: 10.1016/S1097-2765(03)00094-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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