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1LX5

Crystal Structure of the BMP7/ActRII Extracellular Domain Complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
bone morphogenetic protein 7polymer13915699.71UniProt (P18075)
Pfam (PF00019)
Homo sapiens (human)BMP7, Osteogenic protein 1, OP-1
2B
(B)
Activin Type II Receptorpolymer10212019.41UniProt (P27038)
Pfam (PF01064)
Mus musculus (house mouse)ACTR-II
3C
(C)
alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-4)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1073.01In PDB
GlyTouCan (G41943OZ)
4D, E
(B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27719.2
BranchedNumber of molecules1
Total formula weight1073.0
Non-Polymers*Number of molecules2
Total formula weight442.4
All*Total formula weight29234.5
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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