1LB1
Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA
Summary for 1LB1
Entry DOI | 10.2210/pdb1lb1/pdb |
Related | 1FOE 1KI1 1KZ7 1KZG |
Descriptor | Guanine nucleotide exchange factor DBS, Transforming protein RhoA (2 entities in total) |
Functional Keywords | guanine nucleotide exchange factor, small g-protein, rhoa, dbs, dh domain, ph domain, signaling protein |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cytoplasm: Q64096 Cell membrane; Lipid-anchor; Cytoplasmic side: P61586 |
Total number of polymer chains | 8 |
Total formula weight | 251352.43 |
Authors | Snyder, J.T.,Worthylake, D.K.,Rossman, K.L.,Betts, L.,Pruitt, W.M.,Siderovski, D.P.,Der, C.J.,Sondek, J. (deposition date: 2002-04-01, release date: 2002-05-29, Last modification date: 2023-08-16) |
Primary citation | Snyder, J.T.,Worthylake, D.K.,Rossman, K.L.,Betts, L.,Pruitt, W.M.,Siderovski, D.P.,Der, C.J.,Sondek, J. Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9:468-475, 2002 Cited by PubMed: 12006984DOI: 10.1038/nsb796 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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