1LB1
Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | Guanine nucleotide exchange factor DBS | polymer | 353 | 41252.3 | 4 | UniProt (Q64096) Pfam (PF00621) Pfam (PF22697) In PDB | Mus musculus (house mouse) | DBL'S BIG SISTER, DBS |
2 | B, D, F, H | Transforming protein RhoA | polymer | 192 | 21585.8 | 4 | UniProt (P61586) Pfam (PF00071) In PDB | Homo sapiens (human) | H12 |
Sequence modifications
A, C, E, G: 623 - 967 (UniProt: Q64096)
B, D, F, H: 1 - 190 (UniProt: P61586)
PDB | External Database | Details |
---|---|---|
Met 622 | - | SEE REMARK 999 |
Ile 696 | Asn 696 | SEE REMARK 999 |
Phe 697 | Ile 697 | SEE REMARK 999 |
Leu 698 | Pro 698 | SEE REMARK 999 |
Arg 699 | Ala 699 | SEE REMARK 999 |
Glu 700 | Gly 700 | SEE REMARK 999 |
Leu 701 | Val 701 | SEE REMARK 999 |
Glu 968 | - | expression tag |
His 969 | - | expression tag |
His 970 | - | expression tag |
His 971 | - | expression tag |
His 972 | - | expression tag |
His 973 | - | expression tag |
His 974 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | SEE REMARK 999 |
Ala 0 | - | SEE REMARK 999 |
Ser 190 | Cys 190 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 251352.4 | |
All* | Total formula weight | 251352.4 |