1KZO
PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYLATED K-RAS4B PEPTIDE PRODUCT AND FARNESYL DIPHOSPHATE SUBSTRATE BOUND SIMULTANEOUSLY
Summary for 1KZO
Entry DOI | 10.2210/pdb1kzo/pdb |
Related | 1D8D 1FT1 1FT2 1JCQ 1kzp 1kzr |
Descriptor | Protein Farnesyltransferase alpha subunit, Protein Farnesyltransferase beta subunit, Farnesylated K-Ras4B peptide product, ... (8 entities in total) |
Functional Keywords | ftase, pft, pftase, ft, fpt, farnesyltransferase, farnesyl transferase, farnesyl protein transferase, caax, ras, cancer, product, substrate, transferase-transferase substrate complex, transferase/transferase substrate |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 3 |
Total formula weight | 94833.30 |
Authors | Long, S.B.,Casey, P.J.,Beese, L.S. (deposition date: 2002-02-07, release date: 2002-10-16, Last modification date: 2023-08-16) |
Primary citation | Long, S.B.,Casey, P.J.,Beese, L.S. The Reaction Path of Protein Farnesyltransferase at Atomic Resolution Nature, 419:645-650, 2002 Cited by PubMed: 12374986DOI: 10.1038/nature00986 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report