1JOU
Crystal Structure of Native S195A Thrombin with an Unoccupied Active Site
Summary for 1JOU
Entry DOI | 10.2210/pdb1jou/pdb |
Descriptor | Thrombin, light chain, Thrombin, heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | protease, proteinase, thrombin, factor iia, enzyme, blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 107396.20 |
Authors | Huntington, J.A.,Esmon, C.T. (deposition date: 2001-07-31, release date: 2001-08-10, Last modification date: 2023-08-16) |
Primary citation | Huntington, J.A.,Esmon, C.T. The molecular basis of thrombin allostery revealed by a 1.8A structure of the slow form Structure, 11:469-479, 2003 Cited by PubMed: 12679024DOI: 10.1016/S0969-2126(03)00049-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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