1H2U
Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG
Summary for 1H2U
Entry DOI | 10.2210/pdb1h2u/pdb |
Related | 1H2T 1H2V 1H6K |
Descriptor | 80 KDA NUCLEAR CAP BINDING PROTEIN, 20 KDA NUCLEAR CAP BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | m7gcap, cap-binding-complex, rnp domain, mif4g domain, rna maturation, rna export, nuclear protein, rna-binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 205371.67 |
Authors | Mazza, C.,Segref, A.,Mattaj, I.W.,Cusack, S. (deposition date: 2002-08-16, release date: 2002-10-17, Last modification date: 2023-12-13) |
Primary citation | Mazza, C.,Segref, A.,Mattaj, I.W.,Cusack, S. Large-Scale Induced Fit Recognition of an M(7)Gpppg CAP Analogue by the Human Nuclear CAP-Binding Complex Embo J., 21:5548-, 2002 Cited by PubMed: 12374755DOI: 10.1093/EMBOJ/CDF538 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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