1EUB
SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COLLAGENASE-3 (MMP-13) COMPLEXED TO A POTENT NON-PEPTIDIC SULFONAMIDE INHIBITOR
Summary for 1EUB
Entry DOI | 10.2210/pdb1eub/pdb |
Related | 456C 830C |
Descriptor | COLLAGENASE 3, ZINC ION, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | alpha helix, beta sheet, protein-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P45452 |
Total number of polymer chains | 1 |
Total formula weight | 19843.85 |
Authors | Zhang, X.,Gonnella, N.C.,Koehn, J.,Pathak, N.,Ganu, V.,Melton, R.,Parker, D.,Hu, S.I.,Nam, K.Y. (deposition date: 2000-04-14, release date: 2001-04-14, Last modification date: 2024-05-22) |
Primary citation | Zhang, X.,Gonnella, N.C.,Koehn, J.,Pathak, N.,Ganu, V.,Melton, R.,Parker, D.,Hu, S.I.,Nam, K.Y. Solution structure of the catalytic domain of human collagenase-3 (MMP-13) complexed to a potent non-peptidic sulfonamide inhibitor: binding comparison with stromelysin-1 and collagenase-1. J.Mol.Biol., 301:513-524, 2000 Cited by PubMed: 10926524DOI: 10.1006/jmbi.2000.3988 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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