1EGC
STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA
Summary for 1EGC
Entry DOI | 10.2210/pdb1egc/pdb |
Descriptor | MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | acyl-coa dehydrogenase, flavoprotein, electron transfer |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P11310 |
Total number of polymer chains | 4 |
Total formula weight | 181324.17 |
Authors | Lee, H.J.,Wang, M.,Paschke, R.,Nandy, A.,Ghisla, S.,Kim, J.P. (deposition date: 1996-04-11, release date: 1997-11-12, Last modification date: 2024-02-07) |
Primary citation | Lee, H.J.,Wang, M.,Paschke, R.,Nandy, A.,Ghisla, S.,Kim, J.J. Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity. Biochemistry, 35:12412-12420, 1996 Cited by PubMed: 8823176DOI: 10.1021/bi9607867 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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