1EGC
STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | MEDIUM CHAIN ACYL-COA DEHYDROGENASE | polymer | 396 | 43651.8 | 4 | UniProt (P11310) Pfam (PF02771) Pfam (PF02770) Pfam (PF00441) Pfam (PF08028) | Homo sapiens (human) | |
| 2 | E, G, I, K (A, B, C, D) | OCTANOYL-COENZYME A | non-polymer | 893.7 | 4 | Chemie (CO8) | |||
| 3 | F, H, J, L (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 396 (UniProt: P11310)
| PDB | External Database | Details |
|---|---|---|
| Glu 255 | Thr 280 | engineered mutation |
| Gly 376 | Glu 401 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 174607.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 6717.1 | |
| All* | Total formula weight | 181324.2 |
