1DE7
INTERACTION OF FACTOR XIII ACTIVATION PEPTIDE WITH ALPHA-THROMBIN: CRYSTAL STRUCTURE OF THE ENZYME-SUBSTRATE COMPLEX
Summary for 1DE7
Entry DOI | 10.2210/pdb1de7/pdb |
Descriptor | ALPHA-THROMBIN (LIGHT CHAIN), ALPHA-THROMBIN (HEAVY CHAIN), FACTOR XIII ACTIVATION PEPTIDE (28-37), ... (5 entities in total) |
Functional Keywords | enzyme-substrate complex, alpha-thrombin, factor xiii activation peptide, hydrolase/peptide, blood clotting, hydrolase-hydrolase substrate complex, hydrolase/hydrolase substrate |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 |
Total number of polymer chains | 6 |
Total formula weight | 70065.01 |
Authors | Sadasivan, C.,Yee, V.C. (deposition date: 1999-11-13, release date: 2000-12-13, Last modification date: 2023-08-09) |
Primary citation | Sadasivan, C.,Yee, V.C. Interaction of the factor XIII activation peptide with alpha -thrombin. Crystal structure of its enzyme-substrate analog complex. J.Biol.Chem., 275:36942-36948, 2000 Cited by PubMed: 10956659DOI: 10.1074/jbc.M006076200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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