1D5F

STRUCTURE OF E6AP: INSIGHTS INTO UBIQUITINATION PATHWAY

Summary for 1D5F

• Entry DOI: 10.2210/pdb1d5f/pdb
• Related: 1UBQ
• Descriptor: E6AP HECT CATALYTIC DOMAIN, E3 LIGASE (1 entity in total)
• Functional Keywords: bilobal structure, elongated shape, e3 ligase, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 124621.30

Authors

Huang, L.,Kinnucan, E.,Wang, G.,Beaudenon, S.,Howley, P.M.,Huibregtse, J.M.,Pavletich, N.P. (deposition date: 1999-10-07, release date: 1999-11-17, Last modification date: 2024-02-07)

• Primary citation: Huang, L.,Kinnucan, E.,Wang, G.,Beaudenon, S.,Howley, P.M.,Huibregtse, J.M.,Pavletich, N.P.; Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.; Science, 286:1321-1326, 1999; PubMed: 10558980; DOI: 10.1126/science.286.5443.1321

Experimental method

X-RAY DIFFRACTION (2.8 Å)