1B2G
PH AFFECTS GLU B13 SWITCHING AND SULFATE BINDING IN CUBIC INSULIN CRYSTALS (PH 9.00 COORDINATES)
Summary for 1B2G
| Entry DOI | 10.2210/pdb1b2g/pdb |
| Related | 1B17 1B18 1B19 1B2A 1B2B 1B2C 1B2D 1B2E 1B2F 1B2G |
| Descriptor | PROTEIN (INSULIN a chain), PROTEIN (INSULIN b chain) (3 entities in total) |
| Functional Keywords | hormone, hormone-growth factor complex, hormone/growth factor |
| Biological source | Sus scrofa (pig) More |
| Total number of polymer chains | 2 |
| Total formula weight | 5787.63 |
| Authors | Diao, J.S.,Caspar, D.L.D. (deposition date: 1998-11-26, release date: 2003-04-08, Last modification date: 2024-11-06) |
| Primary citation | Diao, J. Crystallographic titration of cubic insulin crystals: pH affects GluB13 switching and sulfate binding. Acta Crystallogr.,Sect.D, 59:670-676, 2003 Cited by PubMed Abstract: Structures of porcine insulin crystals soaked in 1 M sodium sulfate at pH 5.00, 5.53, 5.80, 6.00, 6.16, 6.26, 6.35, 6.50, 6.98 and 9.00 have been determined at between 1.7 and 1.9 A resolution. GluB13 exhibits a single conformation at pH PubMed: 12657786 DOI: 10.1107/S0907444903002208 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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