12OZ

Single particle cryo-EM structure of human MTCH2 (hyperactive mutant F285N F286N)

Summary for 12OZ

• Entry DOI: 10.2210/pdb12oz/pdb
• EMDB information: 76656
• Descriptor: Mitochondrial carrier homolog 2,Mitochondrial brown fat uncoupling protein 1, UCP1 Nanobody (2 entities in total)
• Functional Keywords: mitochondrial outer membrane insertase, slc25 carrier fold, hydrophilic groove, membrane protein biogenesis, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47404.59

Authors

Luo, Z.,Stevens, T.A.,Voorhees, R.M. (deposition date: 2026-04-14, release date: 2026-05-13)

• Primary citation: Luo, Z.,Stevens, T.A.,Lee, C.A.,Hazu, M.,Galatis, E.G.,Inglis, A.J.,Guna, A.,Voorhees, R.M.; Structural evolution of the MTCH family of mitochondrial insertases; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)