11YC

The structure of human Vacuolar Protein Sorting 34 catalytic domain bound to RD-II-123

This is a non-PDB format compatible entry.

Summary for 11YC

• Entry DOI: 10.2210/pdb11yc/pdb
• Related: 9dkp 9orm 9zf4
• Descriptor: Phosphatidylinositol 3-kinase catalytic subunit type 3, (8S)-3-(6-butyl-1,3-benzothiazol-2-yl)pyrazolo[1,5-a]pyrimidine, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: phosphatidylinositol 3-phosphate, lipid regulator, autophagy, membrane trafficking, endocytosis, enzyme, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 68768.27

Authors

Cartwright, J.J.,Abiodun, W.O.,Peterson, M.A.,Moody, J.D. (deposition date: 2026-03-17, release date: 2026-03-25)

• Primary citation: Abiodun, W.O.,Litchfield, C.M.,Burtch, M.,Cartwright, J.,Dass, R.,Singleton, J.D.,Doukov, T.,Peterson, M.A.,Moody, J.D.; The structure of human Vacuolar Protein Sorting 34 catalytic domain bound to RD-II-123; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.41 Å)