11SS

Cryo-EM structure of DNA polymerase Zeta with RNA:DNA hybrid and incoming dNTP

Summary for 11SS

Entry DOI	10.2210/pdb11ss/pdb
EMDB information	76020
Descriptor	DNA polymerase zeta catalytic subunit, IRON/SULFUR CLUSTER, DNA polymerase zeta processivity subunit, ... (11 entities in total)
Functional Keywords	protein complex, dna binding protein, dna binding protein-dna-rna complex, dna binding protein/dna/rna
Biological source	Saccharomyces cerevisiae (brewer's yeast) More
Total number of polymer chains	8
Total formula weight	458377.75
Authors	Malik, R.,Aggarwal, A.K. (deposition date: 2026-03-11, release date: 2026-10-07)
Primary citation	Malik, R.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. Molecular basis of DNA polymerase zeta's reverse transcriptase activity Nat Commun, 2026 Cited by DOI: 10.1038/s41467-026-78032-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.03 Å)

Structure validation