11RL

CryoEM structure of the human origin recognition complex with DNA and CDC6 protein

Summary for 11RL

Entry DOI	10.2210/pdb11rl/pdb
EMDB information	75978
Descriptor	Origin recognition complex subunit 2, MAGNESIUM ION, Origin recognition complex subunit 4, ... (10 entities in total)
Functional Keywords	origin recognition complex, orc, origin licensing, wh domain, atpase, replication, protein-dna complex
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	448834.51
Authors	Chouhan, O.P.,Joshua Tor, L. (deposition date: 2026-03-10, release date: 2026-09-30)
Primary citation	Bauer, J.,Zali, N.,Chouhan, O.P.,El Demerdash, O.,Loell, K.,Kinney, J.,Joshua-Tor, L.,Stillman, B. Evolution of Origin Sequence and Recognition for Licensing of Eukaryotic DNA Replication To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation