11RL
CryoEM structure of the human origin recognition complex with DNA and CDC6 protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Origin recognition complex subunit 2 | polymer | 577 | 66063.4 | 1 | UniProt (Q13416) | Homo sapiens (human) | |
| 2 | B (D) | Origin recognition complex subunit 4 | polymer | 436 | 50443.3 | 1 | UniProt (O43929) | Homo sapiens (human) | |
| 3 | C (H) | DNA (29-MER) | polymer | 60 | 18630.8 | 1 | DNA molecule | ||
| 4 | D (I) | DNA (29-MER) | polymer | 60 | 18364.7 | 1 | DNA molecule | ||
| 5 | E (A) | Origin recognition complex subunit 1 | polymer | 862 | 97556.9 | 1 | UniProt (Q13415) | Homo sapiens (human) | Replication control protein 1 |
| 6 | F (C) | Origin recognition complex subunit 3 | polymer | 712 | 82422.1 | 1 | UniProt (Q9UBD5) | Homo sapiens (human) | Origin recognition complex subunit Latheo |
| 7 | G (E) | Origin recognition complex subunit 5 | polymer | 435 | 50349.9 | 1 | UniProt (O43913) | Homo sapiens (human) | |
| 8 | H (G) | Cell division control protein 6 homolog | polymer | 561 | 62877.4 | 1 | UniProt (Q99741) | Homo sapiens (human) | CDC6-related protein,Cdc18-related protein,HsCdc18,p62(cdc6),HsCDC6 |
| 9 | I, K, M, O (D, A, E, G) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 10 | J, L, N, P (D, A, E, G) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) |
Sequence modifications
A: 1 - 861 (UniProt: Q13415)
C: 1 - 711 (UniProt: Q9UBD5)
G: 1 - 560 (UniProt: Q99741)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 446708.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2125.9 | |
| All* | Total formula weight | 448834.5 |
