11ON

Structural Insights into HIV-1 Vif-Mediated Ubiquitination and Degradation of APOBEC3H

Summary for 11ON

• Entry DOI: 10.2210/pdb11on/pdb
• EMDB information: 75888
• Descriptor: single-stranded DNA cytosine deaminase, Core-binding factor subunit beta, Virion infectivity factor, ... (8 entities in total)
• Functional Keywords: apobec3h, hiv-2 vif, viral protein
• Biological source: Pan troglodytes (chimpanzee); More
• Total number of polymer chains: 8
• Total formula weight: 118100.37

Authors

Matsuo, H.,Skorupka, K.A. (deposition date: 2026-03-06, release date: 2026-10-14)

• Primary citation: Skorupka, K.A.,Matsuoka, K.,Imahashi, M.,Yokomaku, Y.,Iwatani, Y.,Matsuo, H.; Divergent interfaces and convergent outcome in the structural basis of HIV-2 Vif antagonism of APOBEC3H; Nat Commun, 2026; DOI: 10.1038/s41467-026-78197-2

Experimental method

ELECTRON MICROSCOPY (3.1 Å)