11ON
Structural Insights into HIV-1 Vif-Mediated Ubiquitination and Degradation of APOBEC3H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | single-stranded DNA cytosine deaminase | polymer | 185 | 21912.3 | 2 | UniProt (B7T0U6) | Pan troglodytes (chimpanzee) | |
| 2 | B (o) | Core-binding factor subunit beta | polymer | 170 | 20272.6 | 1 | UniProt (Q13951) | Homo sapiens (human) | CBF-beta,Polyomavirus enhancer-binding protein 2 beta subunit,PEA2-beta,PEBP2-beta,SL3-3 enhancer factor 1 subunit beta,SL3/AKV core-binding factor beta subunit |
| 3 | D (p) | Virion infectivity factor | polymer | 216 | 25137.5 | 1 | UniProt (A0A173DUN4) | Human immunodeficiency virus 2 | |
| 4 | E (m) | Elongin-B | polymer | 102 | 11488.0 | 1 | UniProt (Q15370) | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 5 | F (n) | Elongin-C | polymer | 96 | 10843.4 | 1 | UniProt (Q15369) | Homo sapiens (human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 6 | G (C) | RNA | polymer | 10 | 3194.9 | 1 | Escherichia coli BL21(DE3) | ||
| 7 | H (D) | RNA | polymer | 10 | 3143.0 | 1 | Escherichia coli BL21(DE3) | ||
| 8 | I, J, K (A, B, p) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) PubChem (32051) |
Sequence modifications
A, B: 1 - 183 (UniProt: B7T0U6)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 117904.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 118100.4 |
