11HT

Cryo-EM structure of the human ZNFX1 tetramer

Summary for 11HT

• Entry DOI: 10.2210/pdb11ht/pdb
• EMDB information: 75702
• Descriptor: NFX1-type zinc finger-containing protein 1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (2 entities in total)
• Functional Keywords: rna helicase, e3 ligase, rna
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 1325314.99

Authors

Wang, F.,He, Q.,Li, H. (deposition date: 2026-02-25, release date: 2026-10-07)

• Primary citation: He, Q.,Wang, F.,Rassool, F.V.,Baylin, S.B.,Li, H.; Cryo-EM structures of autoinhibited and RNA-activated ZNFX1 helicase; Nat Commun, 2026; DOI: 10.1038/s41467-026-78145-0

Experimental method

ELECTRON MICROSCOPY (3.71 Å)