11HT
Cryo-EM structure of the human ZNFX1 tetramer
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 808 |
| Details | Domain: {"description":"UPF1-type SF1B helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01433","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 88 |
| Details | Zinc finger: {"description":"NF-X1-type 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 64 |
| Details | Zinc finger: {"description":"NF-X1-type 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 72 |
| Details | Zinc finger: {"description":"NF-X1-type 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 744 |
| Details | Region: {"description":"Armadillo-type fold","evidences":[{"source":"PubMed","id":"40876457","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9EVE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 80 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 432 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 40 |
| Details | Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01433","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 76 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39333773","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"9Q9Z","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
