11GN

Crystal structure of mSTING in complex with 3'3'-di-AMP

Summary for 11GN

• Entry DOI: 10.2210/pdb11gn/pdb
• Descriptor: Stimulator of interferon genes protein, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: innate immunity, cgas-sting, complex, immune system
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 4
• Total formula weight: 86299.18

Authors

Kranzusch, P.J.,Li, Y. (deposition date: 2026-02-23, release date: 2026-07-29)

• Primary citation: Kranzusch, P.J.,Li, Y.; Crystal structure of mSTING in complex with 3'3'-di-AMP; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.29 Å)