10SL

Crystal Structure of serine/threonine-protein kinase (AEK1) from Trypanosoma cruzi in complex with Hesperadin

Summary for 10SL

• Entry DOI: 10.2210/pdb10sl/pdb
• Descriptor: Putative rac serine-threonine kinase, N-[2-OXO-3-((E)-PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]IMINO}METHYL)-2,6-DIHYDRO-1H-INDOL-5-YL]ETHANESULFONAMIDE, MALONATE ION, ... (4 entities in total)
• Functional Keywords: ssgcid, structural genomics, seattle structural genomics center for infectious disease, serine/threonine-protein kinase, transferase
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 2
• Total formula weight: 84593.89

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2026-02-05, release date: 2026-02-25)

• Primary citation: Liu, L.,Lovell, S.,Battaile, K.P.; Crystal Structure of serine/threonine-protein kinase (AEK1) from Trypanosoma cruzi in complex with Hesperadin; To be published,

Experimental method

X-RAY DIFFRACTION (2.72 Å)