10NK

Xenopus KCNQ1 Intermediate State (E1R/R2E) in complex with UCL2077

This is a non-PDB format compatible entry.

Summary for 10NK

• Entry DOI: 10.2210/pdb10nk/pdb
• EMDB information: 75305
• Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1, 1,1,1-triphenyl-N-[(pyridin-3-yl)methyl]methanamine (3 entities in total)
• Functional Keywords: potassium ion channel protein, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 317611.64

Authors

Kyriakis, E.,Eldstrom, J.,Van Petegem, F.,Fedida, D. (deposition date: 2026-01-28, release date: 2026-09-02)

• Primary citation: Kyriakis, E.,Roscioni, A.,Eldstrom, J.,Sastre, D.,Dou, Y.,Taddei, A.,Molinarolo, S.,Tian, M.,Maragliano, L.,Van Petegem, F.,Fedida, D.; Structural and kinetic mechanisms of state-dependent potassium channel inhibition; Sci Adv, 2026

Experimental method

ELECTRON MICROSCOPY (3.95 Å)