10NK
Xenopus KCNQ1 Intermediate State (E1R/R2E) in complex with UCL2077
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F (B, D, C, E) | Calmodulin-1 | polymer | 149 | 16852.5 | 4 | UniProt (P0DP23) | Homo sapiens (human) | |
| 2 | C, D, G, H (A, G, F, H) | Potassium voltage-gated channel subfamily KQT member 1 | polymer | 545 | 62375.1 | 4 | UniProt (P70057) | Xenopus laevis (African clawed frog) | IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1,KQT-like 1,Voltage-gated potassium channel subunit Kv7.1 |
| 3 | I, J (A, F) | 1,1,1-triphenyl-N-[(pyridin-3-yl)methyl]methanamine | non-polymer | 350.5 | 2 | Chemie (A1C6W) |
Sequence modifications
A, G, F, H: 66 - 610 (UniProt: P70057)
| PDB | External Database | Details |
|---|---|---|
| Met 66 | Val 66 | conflict |
| Arg 150 | Glu 150 | engineered mutation |
| Glu 221 | Arg 221 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 316910.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 700.9 | |
| All* | Total formula weight | 317611.6 |
