10JG

Structure of Human Argonaute2-miR200b RISC bound to 13nt long target in open conformation

Summary for 10JG

• Entry DOI: 10.2210/pdb10jg/pdb
• EMDB information: 75216
• Descriptor: RNA (5'-R(P*UP*AP*AP*UP*AP*CP*UP*GP*CP*CP*UP*GP*GP*UP*AP*AP*UP*GP*AP*UP*GP*A)-3'), RNA (5'-R(P*CP*CP*UP*AP*UP*CP*AP*GP*UP*AP*UP*UP*A)-3'), Protein argonaute-2 (3 entities in total)
• Functional Keywords: rna binding protein, rna, mirna, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 108528.91

Authors

Garg, A.,Joshua-Tor, L. (deposition date: 2026-01-22, release date: 2026-09-23)

• Primary citation: Garg, A.,Joshua-Tor, L.; Structure of Human Argonaute2-miR200b RISC bound to 13nt long target in open conformation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.6 Å)