9ZVU

The ubiquitin-associated domain of human thirty-eight negative kinase-1 rigidly fused to a double trigger variant of the 1TEL crystallization chaperone, alternate crystal form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transcription factor ETV6,Non-receptor tyrosine-protein kinase TNK1	polymer	165	19304.7	2	UniProt (P41212) UniProt (Q13470) Pfam (PF02198)	Homo sapiens (human)	ETS translocation variant 6,ETS-related protein Tel1,Tel,CD38 negative kinase 1
2	C, D, E, F, L... (A, B)	L(+)-TARTARIC ACID	non-polymer		150.1	7	Chemie (TLA) PubChem (444305)
3	G, H, I, J, P... (A, B)	SODIUM ION	non-polymer		23.0	8	Chemie (NA) PubChem (923)
4	K, T, U (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	O (B)	D(-)-TARTARIC ACID	non-polymer		150.1	1	Chemie (TAR) PubChem (439655)
6	V, W (A, B)	water	water		18.0	121	Chemie (HOH)

Sequence modifications

A, B: 13 - 88 (UniProt: P41212)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 46	Arg 80	engineered mutation
Glu 62	Leu 96	engineered mutation
Glu 78	Val 112	engineered mutation

A, B: 89 - 165 (UniProt: Q13470)

PDB	External Database	Details
Val 90	Leu 591	engineered mutation
Ala 109	Cys 610	engineered mutation
Ala 143	Cys 644	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38609.5
Non-Polymers*	Number of molecules	19
	Total formula weight	1672.8
All*	Total formula weight	40282.3

*Water molecules are not included.