9ZVR
Crystal structure of HTLV-1 protease bound to darunavir at 2.1 angstroms with truncated flaps
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | HTLV-1 Protease | polymer | 116 | 12566.6 | 2 | UniProt (A0A1Y1C9N2) | Human T-cell leukemia virus type I | |
| 2 | C (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 3 | D (B) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 1 | Chemie (017) | |||
| 4 | E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | F, G, H (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 6 | I, J (B, A) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 116 (UniProt: A0A1Y1C9N2)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 66 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25133.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1104.9 | |
| All* | Total formula weight | 26238.1 |
