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9ZP3

E. coli RNA polymerase elongation complex containing the unnatural dP:Z*TP base pair in a trigger-loop-closed conformation.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, G)
DNA-directed RNA polymerase subunit alphapolymer23125526.02UniProt (P0A7Z4)Escherichia coliRNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2C
(I)
DNA-directed RNA polymerase subunit betapolymer1342150820.91UniProt (P0A8V2)Escherichia coliRNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3D
(J)
DNA-directed RNA polymerase subunit beta'polymer1430158105.71UniProt (P0A8T7)Escherichia coliRNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4E
(K)
DNA-directed RNA polymerase subunit omegapolymer748452.61UniProt (P0A800)Escherichia coliRNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5F
(N)
Non-template strand DNApolymer113407.21Escherichia coli
6G
(R)
RNApolymer92934.81Escherichia coli
7H
(T)
Template strand DNApolymer226670.31Escherichia coli
8I, J
(J)
ZINC IONnon-polymer65.42Chemie (ZN)
9K
(J)
[[(2~{R},3~{R},4~{R},5~{S})-5-(5-aminocarbonyl-6-azanyl-2-oxidanylidene-1~{H}-pyridin-3-yl)-4-fluoranyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphatenon-polymer527.21Chemie (A1C49)
10L
(J)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
11M, N, O, P, Q...
(A, G, I, J, K...)
waterwater18.0156Chemie (HOH)
Sequence modifications
J: 1 - 1407 (UniProt: P0A8T7)
PDBExternal DatabaseDetails
Leu 1408-expression tag
Glu 1409-expression tag
Leu 1410-expression tag
Glu 1411-expression tag
Val 1412-expression tag
Leu 1413-expression tag
Phe 1414-expression tag
Gln 1415-expression tag
Gly 1416-expression tag
Pro 1417-expression tag
Ser 1418-expression tag
Ser 1419-expression tag
Gly 1420-expression tag
His 1421-expression tag
His 1422-expression tag
His 1423-expression tag
His 1424-expression tag
His 1425-expression tag
His 1426-expression tag
His 1427-expression tag
His 1428-expression tag
His 1429-expression tag
His 1430-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight381443.6
Non-Polymers*Number of molecules4
Total formula weight682.3
All*Total formula weight382125.9
*Water molecules are not included.

257179

PDB entries from 2026-07-29

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