9ZO8
Structure of RyR1 in presence of rosuvastatin (including auxiliary transmembrane helices TMx1 and TMx2; Ca2+/CFF/ATP dataset; closed pore)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, G, H (E, F, G, H) | Peptidyl-prolyl cis-trans isomerase FKBP1A | polymer | 108 | 11967.7 | 4 | UniProt (P62943) | Oryctolagus cuniculus (rabbit) | PPIase FKBP1A,12 kDa FK506-binding protein,12 kDa FKBP,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase |
| 2 | B, C, D, E (A, B, D, C) | Ryanodine receptor 1 | polymer | 5037 | 565390.4 | 4 | UniProt (P11716) | Oryctolagus cuniculus (rabbit) | RYR-1,RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor |
| 3 | AA, I, P, V (C, A, B, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 4 | BA, J, Q, W (C, A, B, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) PubChem (271) | |||
| 5 | CA, K, R, X (C, A, B, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) PubChem (32051) | |||
| 6 | DA, L, S, Y (C, A, B, D) | CAFFEINE | non-polymer | 194.2 | 4 | Chemie (CFF) PubChem (2519) | |||
| 7 | EA, FA, M, N, O... (C, A, B, D) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 8 | Chemie (PCW) |
Sequence modifications
A, B, D, C: 1 - 5037 (UniProt: P11716)
| PDB | External Database | Details |
|---|---|---|
| Unk 4279 | Ala 4279 | conflict |
| Unk 4280 | Gly 4280 | conflict |
| Unk 4281 | Ala 4281 | conflict |
| Unk 4282 | Glu 4282 | conflict |
| Unk 4283 | Gly 4283 | conflict |
| Unk 4284 | Ala 4284 | conflict |
| Unk 4285 | Ala 4285 | conflict |
| Unk 4286 | Gly 4286 | conflict |
| Unk 4287 | Thr 4287 | conflict |
| Unk 4288 | Val 4288 | conflict |
| Unk 4289 | Ala 4289 | conflict |
| Unk 4290 | Ala 4290 | conflict |
| Unk 4291 | Gly 4291 | conflict |
| Unk 4292 | Ala 4292 | conflict |
| Unk 4293 | Thr 4293 | conflict |
| Unk 4294 | Ala 4294 | conflict |
| Unk 4295 | Arg 4295 | conflict |
| Unk 4296 | Leu 4296 | conflict |
| Unk 4297 | Ala 4297 | conflict |
| Unk 4298 | Ala 4298 | conflict |
| Unk 4299 | Ala 4299 | conflict |
| Unk 4300 | Ala 4300 | conflict |
| Unk 4301 | Ala 4301 | conflict |
| Unk 4302 | Arg 4302 | conflict |
| Unk 4318 | Arg 4318 | conflict |
| Unk 4319 | Leu 4319 | conflict |
| Unk 4320 | Arg 4320 | conflict |
| Unk 4321 | Arg 4321 | conflict |
| Unk 4322 | Leu 4322 | conflict |
| Unk 4323 | Thr 4323 | conflict |
| Unk 4324 | Ala 4324 | conflict |
| Unk 4325 | Arg 4325 | conflict |
| Unk 4326 | Glu 4326 | conflict |
| Unk 4327 | Ala 4327 | conflict |
| Unk 4328 | Ala 4328 | conflict |
| Unk 4329 | Thr 4329 | conflict |
| Unk 4330 | Ala 4330 | conflict |
| Unk 4331 | Leu 4331 | conflict |
| Unk 4332 | Ala 4332 | conflict |
| Unk 4333 | Ala 4333 | conflict |
| Unk 4334 | Leu 4334 | conflict |
| Unk 4335 | Leu 4335 | conflict |
| Unk 4336 | Trp 4336 | conflict |
| Unk 4337 | Ala 4337 | conflict |
| Unk 4338 | Val 4338 | conflict |
| Unk 4339 | Val 4339 | conflict |
| Unk 4340 | Ala 4340 | conflict |
| Unk 4341 | Arg 4341 | conflict |
| Unk 4342 | Ala 4342 | conflict |
| Unk 4343 | Gly 4343 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 2309432.3 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 9524.4 | |
| All* | Total formula weight | 2318956.7 |
