9Z6U

The structure of TMD with 2 TARPs and 2 CNIHs from all native AMPA receptor subtypes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Mix of AMPAR subunit (GluA1, GluA2, GluA3 and GluA4)	polymer	310	29723.6	2		Mus musculus (house mouse)
2	B, D (B, D)	Glutamate receptor 2	polymer	310	29838.8	2	UniProt (P23819)	Mus musculus (house mouse)	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2
3	E, F (E, F)	Mix of Protein cornichon homolog 2 and 3	polymer	159	17901.9	2		Mus musculus (house mouse)
4	G, H (G, H)	Voltage-dependent calcium channel gamma-8 subunit	polymer	422	43371.7	2	UniProt (Q8VHW2)	Mus musculus (house mouse)	Neuronal voltage-gated calcium channel gamma-8 subunit,Transmembrane AMPAR regulatory protein gamma-8,TARP gamma-8
5	AA, BA, CA, FA, HA... (C, D, A, B)	(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate	non-polymer		760.1	20	Chemie (POV)
6	DA, EA, GA, IA, M... (C, D, A, B, E...)	TETRADECANE	non-polymer		198.4	18	Chemie (C14)
7	TA, YA (G, H)	6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol	non-polymer		328.7	2	Chemie (XVD)
8	AB, BB, UA, VA, WA... (H, G)	DODECANE	non-polymer		170.3	6	Chemie (D12)

Sequence modifications

B, D: 508 - 544 (UniProt: P23819)
B, D: 545 - 565 (PDB: 9Z6U)
B, D: 566 - 627 (UniProt: P23819)

PDB	External Database	Details
Arg 583	Gln 607	variant

B, D: 628 - 780 (PDB: 9Z6U)
B, D: 781 - 817 (UniProt: P23819)

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.